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Progress in the Genetics of Severe Mental Illness

Departmental Research Grand Round

Presented by: 

Professor Benjamin NEALE (Associate Professor, Massachusetts General Hospital and Harvard Medical School, Co-director, Stanley Center for Psychiatric Research)

Chaired by:

Professor SHAM Pak Chung (Chair Professor in Psychiatric Genetics, Dept of Psychiatry, SClinMed, HKU)

Date:

14 October 2024

Time:

4:00 am

-

5:00 am

Venue:

Room 211 A&B, 2/F, New Clinical Building, Queen Mary Hospital

Abstract:

A review of recent progress in the genetics of severe mental illness, including 3 priority projects:

(1) Schizophrenia Exome Sequencing Meta-Analysis (SCHEMA) – a global collaborative to generate,

aggregate and harmonize sequence data to advance gene discovery for schizophrenia; (2) Bipolar Exome

(BipEx) collaboration — leveraged exome sequencing in over 14,000 cases to identify AKAP11 as definitive

risk gene for bipolar disorder and schizophrenia; and (3) Populations Underrepresented in Mental Illness

Association Studies (PUMAS) – an international collaboration to discover the genetic risk factors of severe

mental illness in Africa and admixed populations of the Americas

 

Zoom registration link: https://hku.zoom.us/meeting/register/tJcpcuquqjgrE9Ga_oyXzm8rNcN9wGiM-MiP

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